Draft Genome Sequences of Three β-Lactam-Catabolizing Soil Proteobacteria

نویسندگان

  • Terence S. Crofts
  • Bin Wang
  • Aaron Spivak
  • Tara A. Gianoulis
  • Kevin J. Forsberg
  • Molly K. Gibson
  • Lauren A. Johnsky
  • Stacey M. Broomall
  • C. Nicole Rosenzweig
  • Evan W. Skowronski
  • Henry S. Gibbons
  • Morten O. A. Sommer
  • Gautam Dantas
چکیده

Most antibiotics are derived from the soil, but their catabolism there, which is necessary to close the antibiotic carbon cycle, remains uncharacterized. We report the first draft genome sequences of soil Proteobacteria identified for subsisting solely on β-lactams as their carbon sources. The genomes encode multiple β-lactamases, although their antibiotic catabolic pathways remain enigmatic.

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عنوان ژورنال:

دوره 5  شماره 

صفحات  -

تاریخ انتشار 2017